BioMed Laboratory
 School of Life Sciences
 Nanjing University

Jiangning Chen


profchen.jpg陈江宁 博士、教授

博士生导师

办公室: A-434
联系电话:025-89681319
电子邮箱:jnchen@nju.edu.cn

教育及工作经历

1986-1993在南京大学化学系获得化学学士和硕士学位
2001年担任南京大学生命科学学院生物化学系副教授
2003年在南京大学生命科学学院获得生物化学与分子生物学博士学位
2004-2007在美国弗吉尼亚大学医学院做访问研究
2011年至今担任南京大学生命科学学院教授

研究兴趣

炎症性肠病以及炎症相关性疾病的研究
结肠炎-癌转化分子机制研究以及肿瘤分子靶向治疗

讲授课程

《细胞生物学》
《分子生物学进展》
《生物化学分析技术及实验》

获奖情况

2013年南京大学北京银行“京”英奖教金
2011年南京大学优秀教学成果奖一等奖  
2008年教育部双语教学示范课程奖
2002江苏省普通高校优秀课程群奖
2001江苏省高等教育教学成果一等奖

代表论文与著作

1.  Huang, Z.; Ma J.; Chen M.; Jiang H.; Fu Y.; Gan  J.; Dong L.; Zhang, J.; Chen, J.  Dual  TNF-α/IL-12p40  interference as a strategy to protect against colitis based on miR-16  precursors with macrophage targeting vectors  (2015). Molecular  Therapy  doi:  10.1038/mt.2015.111.
2.  Sun,  D., C. Wang, S. Long, Y. Ma, Y. Guo, Z. Huang, X. Chen, C. Zhang, J.  Chen  and J. Zhang (2015). "C/EBP-β-activated  microRNA-223 promotes tumour  growth through targeting RASA1 in human colorectal cancer." Br J Cancer 112(9):  1491-1500.
3.  Zhang  P, He Z, Wang C, Chen  J, Zhao  J, Zhu X, Li C, Min Q, Zhu J (2015). "In Situ  Amplification of Intracellular MicroRNA with MNAzyme Nanodevices for  Multiplexed Imaging, Logic Operation, and Controlled Drug Release."  ACS Nano 9(1):789-98
4. Diao, W.,  F. Jin, B.  Wang, C. Y. Zhang, J.  Chen,  K. Zen and L. Li (2014). "The protective role of myeloid-derived  suppressor cells in concanavalin  A-induced hepatic injury." Protein  Cell 5(9): 714-724.
5. Huang,  Z., T. Shi, Q. Zhou, S. Shi, R. Zhao, H. Shi, L. Dong, C. Zhang, K. Zeng, J.  Chen  and J. Zhang (2013). "miR-141 Regulates colonic leukocytic  trafficking by targeting CXCL12 β during murine colitis and human Crohn's  disease." Gut  63(8):1247-57.
6.  Sun, D., F. Yu, Y. Ma, R. Zhao, X. Chen, J. Zhu, C. Y. Zhang, J.  Chen  and J. Zhang (2013). "MicroRNA-31  activates the RAS pathway and functions as an oncogenic MicroRNA in human  colorectal cancer by repressing RAS p21 GTPase  activating protein 1 (RASA1)." J  Biol  Chem  288(13):  9508-9518.
7.  Zhang,  Z., Y. Zha, W. Hu, Z. Huang, Z. Gao, Y. Zang, J.  Chen,  L.  Dong and J. Zhang (2013). "The autoregulatory  feedback loop of microRNA-21/programmed cell death protein 4/activation  protein-1 (MiR-21/PDCD4/AP-1) as a driving force for hepatic fibrosis  development." J  Biol  Chem  288(52):  37082-37093.
8.  Huang, Z., L. Dong, J. Chen, F. Gao, Z. Zhang, J.  Chen and  J. Zhang (2012). "Low-molecular weight chitosan/vascular endothelial  growth factor short hairpin RNA for the treatment of hepatocellular  carcinoma." Life  Sci  91(23-24):  1207-1215.
9. Chen,  J., H.  Chen, P. Li, H. Diao, S. Zhu, L. Dong, R. Wang, T. Guo, J. Zhao and J. Zhang  (2011). "Simultaneous  regeneration of articular cartilage and subchondral bone in vivo using MSCs  induced by a spatially controlled gene delivery system in bilayered  integrated scaffolds." Biomaterials  32(21): 4793-4805.
10.  Cheng, X., F. Gao, J. Xiang, X. Jiang, J.  Chen  and J. Zhang (2011). "Galactosylated  α,β-poly[(2-hydroxyethyl)-L-aspartamide]-bound doxorubicin: improved  antitumor activity against hepatocellular carcinoma with reduced  hepatotoxicity." Anticancer  Drugs  22(2): 136-147.

最后更新时间:2017-08-18 17:57

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