BioMed Laboratory
 School of Life Sciences
 Nanjing University

Lab-Intro > Director
Director

profzhang.jpg

张峻峰 博士、教授

国家杰出青年基金获得者
   长江学者特聘教授
     博士生导师

办公室:  A-431
     联系电话:025-89682502
     电子邮箱:jfzhang@nju.edu.cn

教育及工作经历

1993-1995中日联合培养在日本京都大学再生医学研究所学习并获博士学位
     1997-2000在新加坡国立大学作研究访问学者
     2001年至今担任南京大学生命科学学院教授

讲授课程

《体内药物输送》
     《化学、生物学与新药发现》

获奖情况

1.2012年长江学者特聘教授
     2.2011年教育部科学技术一等奖
     3.2010年国家杰出青年科学基金
     4.2004年国家自然科学二等奖
     5.2003年教育部科学技术一等奖

代表论文与著作

1.Zhang,  Z., C. Wang, Y. Zha, W. Hu, Z. Gao, Y. Zang, J. Chen, J.  Zhang  and L. Dong (2015). "Corona-directed  nucleic Acid delivery into hepatic stellate cells for liver fibrosis  therapy." ACS  Nano  9(3):  2405-2419.
 2.Tu,  X., H. Zhang, J. Zhang, S. Zhao, X. Zheng, Z. Zhang, J. Zhu, J. Chen, L. Dong,  Y. Zang and  J. Zhang  (2014). "MicroRNA-101  suppresses liver fibrosis by targeting the TGF-β signalling  pathway." J Pathol  234(1):  46-59.
 3.Huang, Z., T. Shi, Q. Zhou, S. Shi, R.  Zhao, H. Shi, L. Dong, C. Zhang, K. Zeng, J. Chen and J.  Zhang  (2013). "miR-141 Regulates colonic leukocytic  trafficking by targeting CXCL12beta during murine colitis and human Crohn's  disease." Gut. 63:1247-57;
 4.Zhang,  Z., Z. Gao, W. Hu, S. Yin, C. Wang, Y. Zang, J. Chen, J.  Zhang  and L. Dong (2013). "3,3'-Diindolylmethane  ameliorates experimental hepatic fibrosis via inhibiting miR-21  expression." Br  J Pharmacol  170(3):  649-660.
 5.Li,  J., Y. Zhang, Y. Liu, X. Dai, W. Li, X. Cai, Y. Yin, Q. Wang, Y. Xue, C. Wang,  D. Li, D. Hou, X. Jiang, J.  Zhang,  K. Zen, X. Chen and C. Y. Zhang (2013). "Microvesicle-mediated  transfer of microRNA-150 from monocytes to endothelial cells promotes  angiogenesis." J Biol  Chem  288(32): 23586-23596.
 6.Yao,  Z., W. Hu, S. Yin, Z. Huang, Q. Zhu, J. Chen, Y. Zang, L. Dong and J.  Zhang (2013).  "3,3'-Diindolymethane  ameliorates adriamycin-induced  cardiac fibrosis via activation of a BRCA1-dependent anti-oxidant  pathway." Pharmacol  Res  70(1):  139-146.
 7.Wang,  R., Z. Wang, Y. Ma, G. Liu, H. Shi, J. Chen, L. Dong, J. Zhao and J.  Zhang  (2013). "Particle-induced  osteolysis  mediated by endoplasmic reticulum stress in prosthesis loosening."  Biomaterials  34(11):  2611-2623.
 8.Sun,  D., F. Yu, Y. Ma, R. Zhao, X. Chen, J. Zhu, C. Y. Zhang, J. Chen and J.  Zhang (2013).  "MicroRNA-31  activates the RAS pathway and functions as an oncogenic MicroRNA in human  colorectal cancer by repressing RAS p21 GTPase  activating protein 1 (RASA1)." J  Biol  Chem  288(13):  9508-9518.
 9.Huang, Z., Y. Yang, Y. Jiang, J. Shao,  X. Sun, J. Chen, L. Dong and J. Zhang  (2013). "Anti-tumor immune responses of tumor-associated macrophages via  toll-like receptor 4 triggered by cationic polymers." Biomaterials  34(3): 746-755.
 10.Yang,  C., C. Wang, X. Chen, S. Chen, Y. Zhang, F. Zhi, J. Wang, L. Li, X. Zhou, N.  Li, H. Pan, J.  Zhang,  K. Zen, C. Y. Zhang and C. Zhang (2013). "Identification of seven serum  microRNAs from a genome-wide serum microRNA expression profile as potential  noninvasive biomarkers for malignant astrocytomas."  Int  J Cancer  132(1): 116-127.
 11.Huang, Z., L. Dong, J. Chen, F. Gao,  Z. Zhang, J. Chen and J.  Zhang  (2012). "Low-molecular weight chitosan/vascular endothelial growth factor  short hairpin RNA for the treatment of hepatocellular carcinoma." Life  Sci  91(23-24):  1207-1215.
 12.Huang, Z., Z. Zhang, Y. Zha, J.  Liu, Y. Jiang, Y. Yang, J. Shao, X. Sun, X. Cai, Y. Yin, J. Chen, L. Dong and  J. Zhang  (2012). "The effect of targeted delivery of anti-TNF-alpha oligonucleotide  into CD169+ macrophages on disease progression in lupus-prone MRL/lpr  mice." Biomaterials  33(30): 7605-7612.
 13.Luo,  Y., Z. Pang, Q. Zhu, X. Cai, Y. Yin, M. Wang, J. Zhu, J. Chen, K. Zeng, C.  Zhang and J.  Zhang  (2012). "Locally  instilled tumor necrosis factor-α antisense oligonucleotide inhibits allergic  inflammation via the induction of Tregs." J  Gene Med  14(6):  374-383.
 14.Chen,  X., H. Liang, J.  Zhang,  K. Zen and C. Y. Zhang (2012). "Horizontal transfer of microRNAs:  molecular mechanisms and clinical applications." Protein  Cell  3(1):  28-37.
 15.Chen,  X., H. Liang, J.  Zhang,  K. Zen and C. Y. Zhang (2012). "Secreted microRNAs: a new form of  intercellular communication." Trends  Cell Biol  22(3): 125-132.
 16.Zhou, G., X. Cheng, S. Wu, X. Jiang,  X. Shi, J. Chen, J.  Zhang  and J. Zhao (2012). "Preparation and antitumor activity of a polymeric  derivative of methotrexate." Am  J Med Sci  344(4):  294-299.
 17.Huang,  Z., Z. Zhang, Y. Jiang, D. Zhang, J. Chen, L. Dong and J.  Zhang  (2012). "Targeted  delivery of oligonucleotides into tumor-associated macrophages for cancer  immunotherapy." J  Control Release  158(2): 286-292.
 18.Zhang,  L., D. Hou, X. Chen, D. Li, L. Zhu, Y. Zhang, J. Li, Z. Bian, X. Liang, X. Cai,  Y. Yin, C. Wang, T. Zhang, D. Zhu, D. Zhang, J. Xu, Q. Chen, Y. Ba, J. Liu, Q.  Wang, J. Chen, J. Wang, M. Wang, Q. Zhang, J.  Zhang,  K. Zen and C. Y. Zhang (2012). "Exogenous plant MIR168a  specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by  microRNA." Cell  Res  22(1):  107-126.

最后更新时间:2017-08-18 15:46